Left Ventricle Assist Device Recovery Should Include Recovery of Ventilatory and Autonomic Nervous System Abnormalities

Myocardial recovery by mechanical unloading with left ventricular assist system.

It has been generally believed that advanced congestive heart failure (HF) is progressive, but there is increasing evidence that mechanical unloading with the use of left ventricular assist system (LVAS) occasionally reverses the progress of HF and permits device explantation. This "bridge to recovery" strategy is attracting interest, not only for the treatment of severe HF, but also in the stu...

acute fulminant myocarditis successfully bridged to recovery with left ventricular assist device and complicated by flail mitral valve

acute fulminant myocarditis is a life-threatening inflammatory disease of the myocardium characterized by the rapid deterioration of the hemodynamic status of the affected individual. with prompt recognition and appropriate management, complete recovery of ventricular function is likely within a few weeks. we introduce a 28-year-old man with acute fulminant myocarditis, who experienced circulat...

Molecular signature of recovery following combination left ventricular assist device (LVAD) support and pharmacologic therapy.

AIMS A novel combination therapy consisting of a left ventricular assist device (LVAD) combined with pharmacologic therapy including the selective beta(2)-agonist, clenbuterol, has shown promise in restoring ventricular function in patients with heart failure. The aim of this study was to identify common genes and signalling pathways whose expression was associated with reversal of heart failur...

Complete explantation of left ventricular assist device due to myocardial recovery.

Theoretical Estimation of Cannulation Methods for Left Ventricular Assist Device Support as a Bridge to Recovery

Left ventricular assist device (LVAD) support under cannulation connected from the left atrium to the aorta (LA-AA) is used as a bridge to recovery in heart failure patients because it is non-invasive to ventricular muscle. However, it has serious problems, such as valve stenosis and blood thrombosis due to the low ejection fraction of the ventricle. We theoretically estimated the effect of the...